Data from the European Chemical Biology Database will be administered by large infrastructures from the Czech Republic

Prague, 26 April 2018. The Institute of Molecular Genetics of the ASCR operates the National Infrastructure for Chemical Biology (CZ-OPENSCREEN). This is our most advanced large research infrastructure in chemical biology and genetics, open to external users. CZ-OPENSCREEN represents the Czech Republic in the European Research Infrastructure Consortium – EU-OPENSCREEN ERIC, whose first meeting was held in Berlin on 12 April.

The meeting confirmed the extraordinary role of CZ-OPENSCREEN in the European Consortium. During the meeting the Institute of Molecular Genetics was selected on the basis of the previous demanding evaluation process as the host institution of the European Chemical Biology Database (ECBD). The hardware background and safe environment of ECBD will be maintained by CESNET – a national e-infrastructure which provides a wide spectre of services for data transmission, storage and processing, and also administers large data storage sites for data storage and sharing. The involvement of CESNET in the ECBD project is an example of the cooperation of large infrastructures at a national level.

All outputs from the partner centres of the EU-OPENSCREEN consortium will be stored in the ECBD, such as data from testing with high throughput screening (HTS) or structures of chemical compounds. All of this data will be made available on the basis of open access to the wider scientific community. Before making the data available, it will undergo the necessary verification and quality check processes before it is released to the public. The validation of the data will be carried out by the partner institutions where the data is initially generated, and then by the ECBD team in Prague.

A user-friendly environment should enable both simple as well as more advanced (with an option to set the exact parameters) search and identification of user-defined data sets. The database will also include tools for the analysis of collected data so that it can be fully utilised both by beginners and advanced users.

In addition to regular user support of the ECBD team, the ECBD web will also offer an interactive guide with a list of primary functions and a description of the displayed data. The gathered verified data will then be transferred from ECBD to the ChEMBL database in order to increase their availability. It will only depend on the scientific community as to how they will use the ECBD data for further research.

The CESNET Association was founded by Czech universities and the Czech Academy of Sciences in 1996. It has built and developed the national CESNET e-infrastructure, designed for science, research and education, including a computer network, computing grids, data repositories and an environment for collaboration and a wide range of offered services for universities, scientific research facilities and other institutions. The Association also does its own research and development of information and communications technology and represents the Czech Republic in major international projects, particularly in building the pan-European GÉANT network. CESNET places great emphasis on the security of network operations, services and user protection.

Last change: 3.5.2018